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Clofibrate
Clofibrate

Artikelnummer: Cay10956-1

Clofibrate is a selective agonist of peroxisome proliferator-activated receptor alpha (PPARalpha). In a transactivation assay, clofibrate exhibits EC50 values of 50 and 55 µM for murine and human PPARalpha, respectively. It also binds to PPARgamma but with 10-fold less affinity and is inactive at PPARdelta at...
Schlagworte: ICI 28257, NSC 79389, 2-(4-chlorophenoxy)-2-methyl-propanoic acid, ethyl ester
Anwendung: PPARalpha agonist
CAS 637-07-0
MW: 242.7 D
ab 27,00 €
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Clofibrate
Clofibrate

Artikelnummer: LKT-C4557.1

A peroxisome proliferator and hypolipidemic drug. Induces apoptosis in hepatoma cells. Also a liver tumor promoter.
Anwendung: Metabolic studies
CAS 637-07-0
MW: 242,7 D
ab 67,00 €
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Clofibrate
Clofibrate

Artikelnummer: TGM-T1298-1g

Description: Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity. Target: PPAR. Smiles: CCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1. References: Casas F, et al. FEBS Lett. 2000, 478(1-2):4-8.
Schlagworte: Clofibrato, Clofibratum, Ethyl clofibrate
Anwendung: Targets peroxisome proliferator-activated receptor alpha (NR1C1, PPARA)
CAS 637-07-0
MW: 242.7 D
ab 42,00 €
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