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Fenobam (hydrate)
Fenobam (hydrate)

Artikelnummer: Cay29759-1

Fenobam is a noncompetitive antagonist and inverse agonist of metabotropic glutamate receptor 5 (mGluR5) that binds to an allosteric site. It inhibits intracellular calcium mobilization induced by the glutamate analog quisqualate (Cay-20211) in HEK293 cells expressing the human receptor (IC50 = 58 nM) and inhibits...
Schlagworte: N-(3-chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)-urea, monohydrate
Anwendung: mGluR5 noncompetitive antagonist / inverse agonist
CAS 63540-28-3
MW: 284.7 D
ab 49,00 €
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Fenobam hydrate
Fenobam hydrate

Artikelnummer: TGM-T68959-10mg

Description: Fenobam hydrate is a noncompetitive antagonist and inverse agonist of metabotropic glutamate receptor 5 (mGluR5). It inhibits intracellular calcium mobilization induced by the glutamate analog quisqualate and inhibits basal activity of mGluR5. Fenobam reduces stress-induced hyperthermia, exhibits...
Anwendung: Targets metabotropic glutamate receptor 5 (GRM5)
CAS 63540-28-3
MW: 284.7 D
ab 106,00 €
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