Zu "634193-54-7" wurden 2 Artikel gefunden!
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L-902,688
Artikelnummer: Cay10007712-1
Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. L-902,688 is a highly potent agonist of the human PGE2 receptor, EP4. It...
| Schlagworte: | 5-[(1E,3R)-4,4-difluoro-3-hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5R-yl)hexyl]-2-pyrrolidinone |
| Anwendung: | EP4 agonist |
| CAS | 634193-54-7 |
| MW: | 419.5 D |
ab 153,00 €
L-902688
Artikelnummer: TGM-T15690-10mg
Description: L-902688 is an orally active EP4 receptor agonist (Ki: 0.38 nM, EC50: 0.6 nM). L-902688 displays >4,000-fold selective for EP4 over other EP and prostanoid receptors. Target: Prostaglandin Receptor. Smiles: C(=C/[C@H](C(F)(F)C1=CC=CC=C1)O)\[C@@H]2N(CCCCCCC=3NN=NN3)C(=O)CC2. References: Lai YJ, et al....
| Anwendung: | EP4 agonist |
| CAS | 634193-54-7 |
| MW: | 419.47 D |
ab 280,00 €
