Zu "622387-85-3" wurden 2 Artikel gefunden!
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Syk Inhibitor
Artikelnummer: Cay14829-1
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that upon phosphorylation binds to immunoreceptor tyrosine-based activation motifs (ITAMs) of FcRgamma chains and mediates downstream signaling related to platelet function and inflammation. Syk inhibitor is an oxindole compound that potently blocks Syk...
| Schlagworte: | OXSI 2, Spleen Tyrosine Kinase, 2,3-dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2-oxo-1H-indole-5-sulfonamide |
| Anwendung: | Spleen Tyrosine Kinase inhibitor |
| CAS | 622387-85-3 |
| MW: | 353.4 D |
ab 49,00 €
OXSI-2
Artikelnummer: TGM-T28281-10mg
Description: OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM. OXSI-2 completely inhibits Adaptor protein LAT Y191 phosphorylation and Syk mediated events in platelets. Target: Syk. Smiles: C(=C1C=2C(NC1=O)=CC=C(S(N)(=O)=O)C2)C=3C=4C(N(C)C3)=CC=CC4. References: Badolia R,...
| Schlagworte: | Syk Inhibitor, OXSI 2 |
| Anwendung: | Spleen Tyrosine Kinase inhibitor |
| CAS | 622387-85-3 |
| MW: | 353.39 D |
ab 106,00 €
