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Dihydroergotamine (mesylate)
Artikelnummer: Cay23847-25
Dihydroergotamine is a derivative of ergotamine and an agonist of the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D (Kis = 0.3 and 2.5 nM, respectively, for human receptors). It binds to dopamine D2 and D3 as well as 5-HT2A receptors (K0.5s = 5, 16, and 38 nM, respectively) but has lower affinity for D1,...
| Schlagworte: | (+)-Dihydroergotamine, (5'alpha,10alpha)-9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-ergotaman-3',6',18-trione,... |
| Anwendung: | alpha1-Adrenergic receptor & serotonin receptor agonist/antagonist, dopamine D2 receptor agonist |
| CAS | 6190-39-2 |
| MW: | 679.8 D |
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