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PKR Inhibitor
Artikelnummer: Cay15323-1
The activity of double-stranded RNA-activated protein kinase (PKR) is altered by viral infection as well as by various neuropathologies. A primary phosphorylation target of PKR is eukaryotic initiation factor 2 subunit alpha (eIF2alpha), blocking translation and driving apoptosis. PKR Inhibitor is an...
| Schlagworte: | C16, GW 506033X, Protein Kinase RNA-activated, 6,8-dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one |
| Anwendung: | EIF2AK2 inhibitor |
| CAS | 608512-97-6 |
| MW: | 268.3 D |
ab 44,00 €
PKR-IN-C16
Artikelnummer: TGM-T16550-100mg
Description: PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210...
| Anwendung: | EIF2AK2 inhibitor |
| CAS | 608512-97-6 |
| MW: | 268.29 D |
ab 37,00 €
