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Oxatomide
Oxatomide

Artikelnummer: Cay42288-10

A histamine H1 receptor antagonist (Ki = 15 nM), selective for the histamine H1 receptor over mAChRs (Ki = 263 nM) but also inhibits 5-HT2 (Ki = 7 nM), inhibits histamine release induced by an anti-IgE antibody in isolated human lung fragments (IC50 = 4.5 nM), inhibits A23187-induced degranulation of RBL-2H3 mast...
Schlagworte: KW 4354, NSC 309710, R 35443, 1-[3-[4-(diphenylmethyl)-1-piperazinyl]propyl]-1,3-dihydro-2H-benzimidazol-2-one
Anwendung: Histamine H1 receptor antagonist
CAS 60607-34-3
MW: 426.6 D
ab 108,00 €
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Oxatomide
Oxatomide

Artikelnummer: TGM-T19839-100mg

Description: Oxatomide (Oxatomida) is a potent and orally active dual H1 histamine receptor and P2X7 receptor antagonist with antihistamine and antiallergic activity.Oxatomide can be used to block ATP-induced currents in the human P2X7 receptor with an IC50 value of 0.95 µM.Oxatomide has an inhibitory effect on...
Schlagworte: Oxatomida
Anwendung: Targets arachidonate 5-lipoxygenase [EC:1.13.11.34] (ALOX5)
CAS 60607-34-3
MW: 426.55 D
ab 31,00 €
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