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Sulindac sulfone
Sulindac sulfone

Artikelnummer: Cay16805-5

Sulindac (Cay-10004386) is a non-steroidal anti-inflammatory drug that has an extensive epidemiology documenting reduced human colorectal cancer. In mouse models, sulindac was found not only to inhibit the enzymatic activity of polyp-associated COX-2, but also to downregulate the expression of colonic COX-2 protein...
Schlagworte: Exisulind, 5-fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic acid
Anwendung: Aldose reductase inhibitor
CAS 59864-04-9
MW: 372.4 D
ab 72,00 €
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Sulindac sulfone
Sulindac sulfone

Artikelnummer: LKT-S8146.250

A metabolite of Sulindac found to inhibit rat colon and mammary carcinogenesis without reducing prostaglandin levels.
Anwendung: Cancer studies
CAS 59864-04-9
MW: 372,4 D
ab 258,00 €
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NEU
Sulindac sulfone
Sulindac sulfone

Artikelnummer: TGM-T23403-100mg

Description: Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac. Sulindac sulfone is an inhibitor of aldose reductase (IC50 =367 nM). Target: COX, Reductase. Smiles: CC1=C(CC(O)=O)c2cc(F)ccc2\C1=C\c1ccc(cc1)S(C)(=O)=O. References: Zheng X, et al. The molecular basis for inhibition...
CAS 59864-04-9
MW: 372.41 D
ab 48,00 €
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