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A 425619
Artikelnummer: TGM-T8562-100mg
Description: A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonist. Target: TRP/TRPV Channel. Smiles: N(C(NCC1=CC=C(C(F)(F)F)C=C1)=O)C=2C3=C(C=CC2)C=NC=C3. References: Chakrabarti S , Pattison L A , Singhal K , et al. Acute inflammation sensitizes knee-innervating sensory...
| Schlagworte: | 1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA |
| CAS | 581809-67-8 |
| MW: | 345.32 D |
ab 76,00 €
A-425619
Artikelnummer: Cay42117-10
A TRPV1 antagonist, selective for TRPV1 over a panel of 83 receptors, enzymes, transporters, and ion channels at 10 µM, inhibits capsaicin-, NADA-, anandamide-, or acid-induced increases in intracellular calcium in HEK293 cells expressing human TRPV1 (IC50s = 5, 4, 3, and 2 nM, respectively), increases core body...
| Schlagworte: | N-5-isoquinolinyl-N'-[[4-(trifluoromethyl)phenyl]methyl]-urea |
| Anwendung: | TRPV1 antagonist |
| CAS | 581809-67-8 |
| MW: | 345.3 D |
ab 208,00 €
