Zu "58-14-0" wurden 2 Artikel gefunden!
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Pyrimethamine
Artikelnummer: TGM-T0849-50mg
Description: Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug. Target: DHFR, Parasite, Antifolate. Smiles: C(C)C=1C(=C(N)N=C(N)N1)C2=CC=C(Cl)C=C2. References: Maegawa GH, et al. J Biol Chem, 2007, 282(12), 9150-9161.
| Schlagworte: | Pirimetamin, RP 4753, Pirimecidan |
| CAS | 58-14-0 |
| MW: | 248.71 D |
ab 40,00 €
Pyrimethamine
Artikelnummer: Cay16472-10
Pyrimethamine is an antiprotozoal agent that is primarily active against P. falciparum, inhibiting the protozoal enzyme dihydrofolate reductase (DHFR). By blocking DHFR activity, pyrimethamine prevents the production of tetrahydrofolic acid, an essential coenzyme involved in DNA and RNA synthesis. In in vivo...
| Schlagworte: | Darapram, Daraprim(R), Khloridin, NSC 3061, 5,4-chlorophenyl-6-ethyl-2,4-pyrimidinediamine |
| Anwendung: | Protozoal dihydrofolate reductase (DHFR) inhibitor |
| CAS | 58-14-0 |
| MW: | 248.7 D |
ab 44,00 €
