Zu "57046-73-8" wurden 3 Artikel gefunden!
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Paprotrain
Artikelnummer: AG-CR1-3504-M001
Cell permeable kinesin-specific MKLP-2 (mitotic kinesin-like protein 2) inhibitor, Inhibits the recruitment of the chromosome passenger proteins survivin and aurora B to the central spindle during anaphase chromosome segregation.
| Schlagworte: | (Z)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile |
| Anwendung: | MKLP-2 (mitotic kinesin-like protein 2) inhibitor |
| CAS | 57046-73-8 |
| MW: | 245,3 D |
99,00 €
Paprotrain
Artikelnummer: Cay10524-1
Mitotic kinesin-like protein 2 (MKLP-2) is an N-terminal motor from the kinesin-6 family that is essential for normal cleavage furrow ingression and cytokinesis. Its activity mediates the relocation of the chromosome passenger proteins Aurora B kinase and survivin from the centromeres to the central spindle in...
| Schlagworte: | Passenger Proteins Transport Inhibitor, alphaZ-(3-pyridinylmethylene)-1H-indole-3-acetonitrile |
| Anwendung: | MKLP-2 inhibitor |
| CAS | 57046-73-8 |
| MW: | 245.3 D |
ab 49,00 €
Paprotrain
Artikelnummer: TGM-T12359-100mg
Description: Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 µM and a Ki of 3.36 µM. Target: Kinesin. Smiles: N#C\C(=C/c1cccnc1)c1c[nH]c2ccccc12. References: Labrière C, et al. Further investigation of Paprotrain:Towards the...
| Schlagworte: | (alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile |
| Anwendung: | MKLP-2 (mitotic kinesin-like protein 2) inhibitor |
| CAS | 57046-73-8 |
| MW: | 245.28 D |
ab 39,00 €
