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BPH-1358
Artikelnummer: TGM-T10586L-100mg
Description: BPH-1358 (NSC-50460) (NSC-50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 µM and 110 nM, respectively. And it is active against S. aureus in vitro (MIC ~250 ng/mL)[1][2]. Target: Others, Antibacterial. Smiles:...
| Schlagworte: | NSC50460 |
| CAS | 5352-53-4 |
| MW: | 601.53 D |
ab 55,00 €
BPH-1358
Artikelnummer: Cay37402-5
BPH-1358 is an inhibitor of undecaprenyl diphosphate synthase (UPPS, IC50 = 0.11 µM for the E. coli and S. aureus enzymes), an enzyme involved in bacterial cell wall biosynthesis. It is also an inhibitor of farnesyl diphosphate synthase (FPPS, IC50 = 1.8 µM for the human enzyme), an enzyme in the mevalonate pathway...
| Schlagworte: | NSC 50460, N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-[1,1'-biphenyl]-4,4'-dicarboxamide |
| Anwendung: | uppS inhibitor |
| CAS | 5352-53-4 |
| MW: | 601.5 D |
ab 118,00 €
