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Rapamycin
Rapamycin

Artikelnummer: AG-CN2-0025-M001

Isolated from Streptomyces hygroscopicus. Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the molecular target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an...
Schlagworte: Sirolimus, Rapamune, NSC 226080, Antibiotic AY-22989, WY-090217, RAPA, SILA 9268A, CCRIS 9024
Anwendung: MTOR inhibitor, Immunsuppressant, Apoptosis inducer
CAS 53123-88-9
MW: 914,2 D
ab 28,00 €
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Rapamycin
Rapamycin

Artikelnummer: Cay13346-1

Rapamycin is an immunosuppressant that is used primarily to prevent the rejection of organ and bone marrow transplant. It was first described as a potent inhibitor of IL-2 activation of lymphocytes (IC50 = 5 pM). It is now known that rapamycin specifically interacts with the cytosolic FK-binding protein 12 (FKBP12)...
Schlagworte: Sirolimus,...
Anwendung: MTORC1 blocking
CAS 53123-88-9
MW: 914.2 D
ab 37,00 €
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Rapamycin
Rapamycin

Artikelnummer: LKT-R0161.10

An antifungal antibiotic that has immunosuppressive activity. It blocks cytokine-mediated signal transduction pathways.
Schlagworte: Sirolimus
Anwendung: Antibiotic
CAS 53123-88-9
MW: 914,17 D
ab 48,00 €
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Rapamycin (FRAP, mTOR Inhibitor)
Rapamycin (FRAP, mTOR Inhibitor)

Artikelnummer: R1137-01.10

Rapamycin is a bacterial macrolide with antifungal and immunosuppressant activities , (1). Rapamycin forms a complex with the immunophilin FKBP12 which then inhibits the activity of FRAP/mTOR (TOR in yeast) (2,3). Rapamycin treatment of cells leads to the dephosphorylation and inactivation of p70 S6 kinase....
CAS 53123-88-9
MW: 914.20 D
ab 98,00 €
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Rapamycin (Sirolimus, RAPA, Rapamune, AY-22989, NSC 226080, LCP-Siro, SILA 9268A, CAS 53123-88-9), >
Rapamycin (Sirolimus, RAPA, Rapamune, AY-22989, NSC...

Artikelnummer: LC-R-5000_50mg

Soluble in DMSO at 200 mg/mL, soluble in ethanol at 50 mg/mL, very poorly soluble in water, maximum solubility in plain water is estimated to be about 5-20 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
Schlagworte: Sirolimus,...
Anwendung: MTORC1 blocking
CAS 53123-88-9
MW: 914,17 D
ab 82,00 €
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