Zu "52665-74-4" wurden 5 Artikel gefunden!
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Manumycin A
Artikelnummer: Cay10010497-1
Manumycin A is an antibiotic that acts as a potent and selective farnesyltransferase (FTase) inhibitor with anti-tumor activity. It inhibits rat brain FTase with a Ki value of 1.2 µM, thereby preventing Ras activation which requires farnesylation at the C-terminus for membrane attachment. It exhibits significant...
| Schlagworte: | NSC 622141, UCF 1C,... |
| Anwendung: | FTase inhibitor |
| CAS | 52665-74-4 |
| MW: | 550.7 D |
ab 166,00 €
Manumycin A
Artikelnummer: LKT-M017545.1
| Schlagworte: | Manumycin-A, 2,4-Decadienamide,... |
| Anwendung: | FTase inhibitor |
| CAS | 52665-74-4 |
| MW: | 550.65 D |
ab 341,00 €
Manumycin A
Artikelnummer: AG-CN2-2000-M010
Antibiotic. Apoptosis and endoplasmic reticulum stress-mediated cell death inducer. Potent, selective and competitive cell permeable rasfarnesyltransferase inhibitor (IC50 = 30 nM). Does not affect geranylgeranyltransferase (IC50 = 180 µM). Inhibition is competitive with respect to farnesyl pyrophosphate and...
| Schlagworte: | Posttranslational Mod. |
| Anwendung: | Rasfarnesyltransferase inhibitor |
| CAS | 52665-74-4 |
| MW: | 550.6 D |
792,00 €
Manumycin A
Artikelnummer: AG-CN2-2000-M001
Antibiotic. Apoptosis and endoplasmic reticulum stress-mediated cell death inducer. Potent, selective and competitive cell permeable rasfarnesyltransferase inhibitor (IC50 = 30 nM). Does not affect geranylgeranyltransferase (IC50 = 180 µM). Inhibition is competitive with respect to farnesyl pyrophosphate and...
| Anwendung: | Antibiotic |
| CAS | 52665-74-4 |
| MW: | 550.6 D |
121,00 €
Manumycin A
Artikelnummer: TGM-T16011-1mg
Description: Manumycin A is an antibiotic with anticancer activity and is a mammalian thioredoxin reductase-1 (TrxR-1) inhibitor.Manumycin A inhibits the production of IL-1beta, IL-6, and IL-8 in TNF alpha-stimulated THP-1 cells and peripheral blood mononuclear cells in a dose-dependent manner, inducing apoptosis....
| Anwendung: | Rasfarnesyltransferase inhibitor |
| CAS | 52665-74-4 |
| MW: | 550.64 D |
ab 262,00 €
