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JNJ-10229570
JNJ-10229570

Artikelnummer: TGM-T5464-100mg

Description: JNJ-10229570 (UNII-N9IX402L35) is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. Target: Melanocortin Receptor. Smiles: COc1ccccc1-c1n\c(=N\c2ccccc2)sn1-c1ccccc1OC....
Schlagworte: JNJ10229570, JNJ 10229570, UNII-N9IX402L35
Anwendung: Melanocortin receptor antagonist
CAS 524923-88-4
MW: 389.47 D
ab 105,00 €
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JNJ-10229570
JNJ-10229570

Artikelnummer: Cay37768-1

JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R), MC4R, and MC5R (IC50s = 270, 240, and 200 nM, respectively, in radioligand binding assays). It prevents bovine pituitary extract-induced increases in lipid droplets in primary human sebocytes when used at a concentration of 0.05 µM. JNJ-10229570 (1 µM)...
Schlagworte: N-[2,3-bis(2-methoxyphenyl)-1,2,4-thiadiazol-5(2H)-ylidene]-benzenamine
Anwendung: Melanocortin receptor antagonist
CAS 524923-88-4
MW: 389.5 D
ab 83,00 €
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