Zu "51987-99-6" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
TGN 020
Artikelnummer: Cay30955-10
TGN 020 is an aquaporin-4 (AQP4) inhibitor (IC50 = 3.1 µM in X. laevis oocytes transfected with AQP4). It reduces brain edema and cortical infarction size in a mouse model of transient focal cerebral ischemia induced by middle cerebral artery occlusion (MCAO) when administered at a dose of 200 mg/kg. TGN 020 (200...
| Schlagworte: | N-1,3,4-thiadiazol-2-yl-3-pyridinecarboxamide |
| Anwendung: | AQP4 inhibitor |
| CAS | 51987-99-6 |
| MW: | 206.2 D |
ab 128,00 €
TGN-020
Artikelnummer: TGM-T5102-100mg
Description: TGN-020 is an inhibitor of Aquaporin 4 (AQP4, IC50: 3.1 µM), the most abundant water channel in the brain. Target: Aquaporin, PROTAC Linker. Smiles: O=C(Nc1nncs1)c1cccnc1. References: Huber VJ, et al. Identification of aquaporin 4 inhibitors using in vitro and in silico methods. Bioorg Med Chem. 2009...
| Schlagworte: | TGN020 |
| Anwendung: | AQP4 inhibitor |
| CAS | 51987-99-6 |
| MW: | 206.22 D |
ab 45,00 €
