Zu "516480-79-8" wurden 3 Artikel gefunden!
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Chk2 Inhibitor II
Artikelnummer: Cay17552-1
Chk2 inhibitor II is a selective, ATP-competitive inhibitor of the DNA damage control kinase, checkpoint kinase 2 (IC50 = 15 nM). It has been shown to prevent apoptosis in human T-cells exposed to ionizing radiation (EC50 = 3-7.6 µM). This compound has been used to target the role of Chk2 in cellular signaling in...
| Schlagworte: | BML-277, C 3742, Checkpoint Kinase 2 Inhibitor II, 2-[4-(4-chlorophenoxy)phenyl]-1H-benzimidazole-6-carboxamide |
| Anwendung: | Checkpoint kinase 2 inhibitor |
| CAS | 516480-79-8 |
| MW: | 363.8 D |
ab 49,00 €
BML-277
Artikelnummer: LKT-B5044.25
Arylbenzimidazole, CHK2 inhibitor.
| Anwendung: | Arylbenzimidazole, CHK2 inhibitor |
| CAS | 516480-79-8 |
| MW: | 363.8 D |
ab 176,00 €
BML-277
Artikelnummer: TGM-T2033-100mg
Description: BML-277 (C 3742) is a selective checkpoint kinase 2 (Chk2) inhibitor. Target: Apoptosis, Chk. Smiles: NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(Oc2ccc(Cl)cc2)cc1. References: Arienti KL, et al. Checkpoint kinase inhibitors: SAR and radioprotective properties of a series of 2-arylbenzimidazoles. J Med Chem. 2005...
| Schlagworte: | C 3742, Chk2 Inhibitor II, BML 277 |
| CAS | 516480-79-8 |
| MW: | 363.8 D |
ab 45,00 €
