Zu "515814-01-4" wurden 2 Artikel gefunden!
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Voclosporin
Artikelnummer: Cay39719-1
Voclosporin is an immunosuppressant and a derivative of cyclosporin A (Cay-12088). It binds to cyclophilin A (Kd = 15 nM) and inhibits calcineurin activity in isolated human whole blood (IC50 = 120 ng/ml). Voclosporin reduces the proliferation of, and production of IL-2, IFN-gamma, and TNF-alpha in, isolated...
| Schlagworte: | (E)-ISA247, trans-ISA 247, ISATX247, LX211, R-15424, 6-[(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic... |
| Anwendung: | Immunosuppressant, calcineurin inhibitor |
| CAS | 515814-01-4 |
| MW: | 1214.6 D |
ab 192,00 €
Voclosporin
Artikelnummer: TGM-T17235-100mg
Description: Voclosporin (ISAtx-247) is a novel, orally available calcium-modulated phosphatase (CN, PP2B) inhibitor and immunosuppressant used for treating lupus nephritis. Target: Phosphatase. Smiles:...
| Schlagworte: | ISAtx-247 |
| Anwendung: | Immunosuppressant, Calcineurin inhibitor |
| CAS | 515814-01-4 |
| MW: | 1214.62 D |
ab 100,00 €
