Zu "515141-51-2" wurden 2 Artikel gefunden!
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GW 803430
Artikelnummer: Cay13948-1
GW 803430 is an antagonist of melanin-concentrating hormone receptor 1 (MCH1, IC50 = 0.5 nM). It reduces cumulative body weight and food intake in diet-induced obese rats when administered at doses of 1 and 3 mg/kg. GW 803430 (10 and 30 mg/kg) decreases marble-burying behavior in mice, indicating anxiolytic...
| Schlagworte: | GW 3430, 6-(4-chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-thieno[3,2-d]pyrimidin-4(3H)-one |
| Anwendung: | MCHR1 antagonist |
| CAS | 515141-51-2 |
| MW: | 482 D |
ab 69,00 €
GW-803430
Artikelnummer: TGM-T15450-100mg
Description: GW-803430 is a potent and selective antagonist of melanin-concentrating hormone receptor 1 (MCH R1) (pIC50: 9.3). GW-803430 is orally active in an animal model of obesity. Target: Others. Smiles: O=C1C2=C(C=C(S2)C3=CC=C(Cl)C=C3)N=CN1C4=CC(OC)=C(OCCN5CCCC5)C=C4. References: Hertzog DL, et al. The...
| Schlagworte: | GW-3430 |
| Anwendung: | MCHR1 antagonist |
| CAS | 515141-51-2 |
| MW: | 481.99 D |
ab 529,00 €
