Zu "504433-23-2" wurden 3 Artikel gefunden!
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GW 441756
Artikelnummer: TGM-T6052-100mg
Description: GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM. Target: Apoptosis, CDK, Raf, Trk receptor. Smiles: Cn1cc(\C=C2/C(=O)Nc3cccnc23)c2ccccc12. References: Wood ER, et al. Bioorg Med Chem Lett, 2004, 14(4), 953-957.
| Anwendung: | TrkA inhibitor |
| CAS | 504433-23-2 |
| MW: | 275.3 D |
ab 52,00 €
GW-441756
Artikelnummer: SYN-1044-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. GW441756 is an orally active, potent and highly selective TrkA tyrosine kinase inhibitor (IC(50) of 2nM). It specifically blocks TrkA-induced cell death in a dose-dependent manner. Target: TrkA , Kinase Group: RTK , Substrate: Tyrosine
| Schlagworte: | GW441756 |
| Anwendung: | TrkA inhibitor |
| CAS | 504433-23-2 |
| MW: | 275,3 D |
ab 92,00 €
GW 441756
Artikelnummer: Cay16915-1
The high affinity nerve growth factor (NGF) receptor, also known as NGF tyrosine kinase receptor A (TrkA), is involved in the development and maturation of the nervous system. Aberrant expression is associated with certain forms of cancer and congenital insensitivity to pain with anhidrosis. GW 441756 is a potent...
| Schlagworte: | 1,3-dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one |
| Anwendung: | TrkA inhibitor |
| CAS | 504433-23-2 |
| MW: | 275.3 D |
ab 34,00 €
