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PHA-408
Artikelnummer: Cay41279-1
PHA-408 is an inhibitor of IkappaB kinase beta (IKKbeta, IC50 = 0.04 µM). It is selective for IKKbeta over IKKalpha, Pim-1, Pim-2, Tie2, TrkA, and p70S6K (IC50s = 0.6-28.4 µM), as well as a panel of 26 kinases (IC50s = >30 µM for all). PHA-408 inhibits IL-1beta-induced production of prostaglandin E2 (PGE2,...
| Schlagworte: | PHA-767408,... |
| Anwendung: | IKKbeta inhibitor |
| CAS | 503555-55-3 |
| MW: | 560 D |
ab 44,00 €
PHA-408
Artikelnummer: TGM-T24629-100mg
Description: PHA-408 is a novel potent, highly selective and ATP-competitive inhibitor of IKB kinase-2. Target: Others. Smiles: CN1CCN(CC1)c1cc(C(=O)Nc2ccc3CCc4c(nn(c4-c3c2)-c2ccc(F)cc2)C(N)=O)c(Cl)cn1. References: Lai CY, Su YW, Lin KI, Hsu LC, Chuang TH. Natural Modulators of Endosomal Toll-Like Receptor-Mediated...
| Schlagworte: | PHA 408 |
| Anwendung: | IKKbeta inhibitor |
| CAS | 503555-55-3 |
| MW: | 560.02 D |
ab 1.440,00 €
