Zu "501919-59-1" wurden 3 Artikel gefunden!
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S3I-201
Artikelnummer: Cay14336-5
Signal transducers and activators of transcription (STATs) are a family of latent cytoplasmic transcription factors that convey signals from the cell membrane to the nucleus. In various human tumors, STAT3 is constitutively activated by aberrant upstream tyrosine kinase activities. STAT signaling is also suspected...
| Schlagworte: | NSC 74859, 2-hydroxy-4-[[2-[[(4-methylphenyl)sulfonyl]oxy]acetyl]amino]-benzoic acid |
| Anwendung: | STAT3 inhibitor |
| CAS | 501919-59-1 |
| MW: | 365.4 D |
ab 95,00 €
NSC-74859
Artikelnummer: LKT-N7208.100
NSC-74859 is an inhibitor of pSTAT3 that exhibits anticancer chemotherapeutic, antiviral, anti-fibrotic, and nephroprotective activities. NSC-74859 enhances the toxicity of doxorubicin by inhibiting the epithelial-to-mesenchymal transition (EMT) in vitro, it also enhances the efficacy of cetuximab in hepatic...
| Schlagworte: | S3I-201 |
| Anwendung: | STAT3 inhibitor |
| CAS | 501919-59-1 |
| MW: | 365.36 D |
ab 109,00 €
S3I-201
Artikelnummer: TGM-T2505-100mg
Description: S3I-201 (S3I-201) is a selective Stat3 inhibitor (IC50: 86±33 µM) and low effect towards STAT1/5. Target: STAT. Smiles: Cc1ccc(cc1)S(=O)(=O)OCC(=O)Nc1ccc(C(O)=O)c(O)c1. References: Siddiquee K, et al. Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening,...
| Schlagworte: | S3I201, S3I 201 |
| Anwendung: | STAT3 inhibitor |
| CAS | 501919-59-1 |
| MW: | 365.36 D |
ab 48,00 €
