Zu "500-92-5" wurden 2 Artikel gefunden!
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Proguanil
Artikelnummer: Cay30675-10
Proguanil is a prodrug form of the antimalarial agent cycloguanil (Cay-16861). Proguanil is metabolized by the cytochrome P450 (CYP) isoforms CYP2C19 and CYP3A to form cycloguanil in human liver microsomes. It is active against chloroquine- and quinine-resistant strains of P. falciparum alone or in combination with...
| Schlagworte: | Chlorguanide, Chloroguanide, N-(4-chlorophenyl)-N'-(1-methylethyl)-imidodicarbonimidic diamide |
| Anwendung: | Cycloguanil prodrug |
| CAS | 500-92-5 |
| MW: | 253.7 D |
ab 72,00 €
Proguanil
Artikelnummer: TGM-T22409-5mg
Description: Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the dihydrofolate reductase (DHFR) enzyme of Plasmodium falciparum, preventing the synthesis of purines and pyrimidines and inhibiting the growth and reproduction...
| Schlagworte: | Chloroguanide , Chlorguanide |
| Anwendung: | Targets dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45] (DHFR-TS) |
| CAS | 500-92-5 |
| MW: | 253.73 D |
ab 34,00 €
