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A1899
Artikelnummer: TGM-T24993-25mg
Description: A1899 is a effective and selective TASK-1 and TASK-3 antagonist. Target: Others. Smiles: C(NC(CC1=CC=C(OC)C=C1)=O)C2=C(C=CC=C2)C3=C(C(NCC4=C(F)C=C(F)C=C4)=O)C=CC=C3. References: Ramírez D, Arévalo B, Martínez G, Rinné S, Sepúlveda FV, Decher N, González W. Side Fenestrations Provide an "Anchor" for a...
| Schlagworte: | S 20951, S20951, A-1899, A 1899, S-20951 |
| CAS | 498577-46-1 |
| MW: | 500.54 D |
ab 373,00 €
A-1899
Artikelnummer: Cay43018-50
A-1899 is an inhibitor of the two-pore domain potassium channel 3. (K2P3.1/TASK1, IC50 = 0. µM in Xenopus oocytes expressing the human channel). It is selective for K2P3.1/TASK1 over K2P5.1/TASK2, K2P9.1/TASK3, and K2P17.1/TASK4 (IC50s = 12, 0. and 8. µM, respectively) and a panel of 16 additional potassium channels...
| Schlagworte: | S-20951, N-[(2,4-difluorophenyl)methyl]-2'-[[[2-(4-methoxyphenyl)acetyl]amino]methyl]-[1,1'-biphenyl]-2-carboxamide |
| Anwendung: | K2P3.1/TASK1/KCNK3 inhibitor |
| CAS | 498577-46-1 |
| MW: | 500.55 D |
ab 53,00 €
