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Sulindac sulfide
Artikelnummer: TGM-T13037-10mg
Description: Sulindac sulfide (cis-Sulindac sulfide) is a non-steroidal anti-inflammatory compound that has a high affinity for COX-1 and acts as an inhibitor in Ras activation of Raf-1. Sulindac sulfide is a non-competitive inhibitor of gamma-secretase with an IC50 value of 20.2 µM. It is an active metabolite of...
| Schlagworte: | cis-Sulindac sulfide |
| Anwendung: | Aldose reductase inhibitor, COX1/COX2 inhibitor |
| CAS | 49627-27-2 |
| MW: | 340.41 D |
ab 31,00 €
Sulindac sulfide
Artikelnummer: Cay10004387-10
Sulindac sulfide is an active metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor sulindac (Item No, 10004386). It inhibits both COX-1 and COX-2 (IC50s = 1.9 and 1.21 µM, respectively), whereas the parent compound, sulindac, is much less effective (IC50 = 58 µM for COX-2 and > 100 µM for...
| Schlagworte: | 5-fluoro-2-methyl-1Z-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid |
| Anwendung: | Aldose reductase inhibitor, COX1/COX2 inhibitor |
| CAS | 49627-27-2 |
| MW: | 340.4 D |
ab 44,00 €
