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CBFbeta Inhibitor
Artikelnummer: Cay16771-5
Core binding factors (CBFs) are heterodimeric transcription factors consisting of a DNA-binding CBFalpha component (a RUNX protein) and an enhancer of binding, CBFbeta. CBF dimers have central roles in hematopoiesis and, when dysfunctional, in leukemias. CBFbeta inhibitor is a small molecule that binds to CBFbeta...
| Schlagworte: | Core Binding Factor-beta Inhibitor, 5-ethyl-4-(4-methoxyphenyl)-2-thiazolamine |
| Anwendung: | CBFbeta-Runx1 interaction inhibitor |
| CAS | 493028-20-9 |
| MW: | 234.3 D |
ab 112,00 €
CBFbeta Inhibitor
Artikelnummer: TGM-T22195-10mg
Description: CBFbeta Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFbeta inhibitor and inhibits its association with Runx1. Target: DNA/RNA Synthesis. Smiles: CCC1=C(N=C(N)S1)C1=CC=C(OC)C=C1. References: Michael J Gorczynskir, et al.Allosteric inhibition of the protein-protein...
| Schlagworte: | 5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine |
| Anwendung: | CBFbeta inhibitor |
| CAS | 493028-20-9 |
| MW: | 234.32 D |
ab 29,00 €
