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TCS PIM-1 1
Artikelnummer: TGM-T2253-100mg
Description: TCS PIM-1 1 (SC 204330)(sc-204330) is an effective and specific ATP-competitive Pim-1 kinase inhibitor (IC50: 50 nM), exhibiting good specificity over MEK1/MEK2 and Pim-2 (IC50s > 20,000 nM). Target: Pim. Smiles: Oc1ccc(Br)cc1-c1cc(-c2ccccc2)c(C#N)c(=O)[nH]1. References: Cheney IW, et al. Bioorg Med...
| Schlagworte: | SC 204330 |
| Anwendung: | PIM1 inhibitor |
| CAS | 491871-58-0 |
| MW: | 367.2 D |
ab 30,00 €
TCS PIM-1 1
Artikelnummer: Cay16286-10
The proto-oncogene serine/threonine-protein kinases, Pim-1 and Pim-2, are enzymes involved in cytokine signaling and participate in various signal transduction pathways, including cell growth, differentiation, and apoptosis. Their overexpression has been implicated in prostate cancer, some forms of leukemia, and...
| Schlagworte: | Pim-1 Kinase Inhibitor II, SC-204330, 6-(5-bromo-2-hydroxyphenyl)-1,2-dihydro-2-oxo-4-phenyl-3-pyridinecarbonitrile |
| Anwendung: | PIM1 inhibitor |
| CAS | 491871-58-0 |
| MW: | 367.2 D |
ab 149,00 €
