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SBC-115076
Artikelnummer: TGM-T2626-100mg
Description: SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist. Target: Serine/threonin kinase, Others. Smiles: Cc1cc(ccc1OCc1ccccc1)C(=O)C1=C(O)C(=O)N(CCCN2CCOCC2)C1c1ccncc1. References: Abdel-Meguid SS, et al. WO2014150326 A1.
| Schlagworte: | SBC115076 |
| Anwendung: | PCSK9 inhibitor |
| CAS | 489415-96-5 |
| MW: | 527.61 D |
ab 34,00 €
SBC-115076
Artikelnummer: Cay19134-1
Proprotein convertase subtilisin kexin 9 (PCSK9) is a member of the subtilisin serine protease family with important roles in lipoprotein metabolism. PCSK9 overexpression in wild-type mice doubles plasma total cholesterol, possibly through acceleration of degradation of the LDL receptor (LDLR). SBC-115076 is an...
| Schlagworte: | 1,5-dihydro-3-hydroxy-4-[3-methyl-4-(phenylmethoxy)benzoyl]-1-[3-(4-morpholinyl)propyl]-5-(4-pyridinyl)-2H-pyrrol-2-one |
| Anwendung: | PCSK9 inhibitor |
| CAS | 489415-96-5 |
| MW: | 527.6 D |
ab 44,00 €
