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LC3-mHTT-IN-AN1
Artikelnummer: TGM-T8081-100mg
Description: LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 targeted mHTT to autophagosomes reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons. Target: Autophagy, Others,...
| Anwendung: | LC3B-mutant huntingtin linker |
| CAS | 486443-73-6 |
| MW: | 411.04 D |
ab 37,00 €
LC3-mHTT-IN-AN1
Artikelnummer: Cay34306-1
LC3-mHTT-IN-AN1 is a linker molecule that interacts with the autophagosome protein microtubule-associated protein 1 light chain 3beta (LC3B) and mutant huntingtin (Hdh). It decreases HdhQ7/Q140, but not wild-type huntingtin, levels in primary mouse cortical neurons when used at a concentration of 300 nM....
| Schlagworte: | 5-bromo-3-[(3-bromo-4,5-dihydroxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one |
| Anwendung: | LC3B-mutant huntingtin linker |
| CAS | 486443-73-6 |
| MW: | 411 D |
ab 45,00 €
