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AZD 2858
Artikelnummer: Cay16728-1
Glycogen synthase kinase 3beta (GSK3beta) was originally identified for its ability to constitutively phosphorylate and inactivate glycogen synthase, preventing glycogen synthesis. It can also phosphorylate proteins that are relevant to osteogenesis and Alzheimer's disease, the latter for which it has earned the...
| Schlagworte: | 3-amino-6-[4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-N-3-pyridinyl-2-pyrazinecarboxamide |
| Anwendung: | GSK3beta inhibitor |
| CAS | 486424-20-8 |
| MW: | 453.5 D |
ab 50,00 €
AZD2858
Artikelnummer: TGM-T1957-100mg
Description: AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating Wnt signaling pathway. Target: GSK-3. Smiles: C(NC=1C=CC=NC1)(=O)C=2N=C(C=NC2N)C3=CC=C(S(=O)(=O)N4CCN(C)CC4)C=C3. References: Marsell R, et al. Bone, 2012, 50(3), 619-627.
| Anwendung: | GSK3beta inhibitor |
| CAS | 486424-20-8 |
| MW: | 453.52 D |
ab 31,00 €
