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RK-20448
Artikelnummer: Cay25606-5
RK-20448 is an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R, and Tie-2 (IC50s = 0.24, 1.19, 10.74, and 5.85 µM, respectively). It also inhibits BLK, Csk, Fyn, and Lyn (IC50s = 0.37, 4.27, 2.03, and 0.43 µM, respectively). RK-20448 is the cis isomer of A-419259 (Cay-18168).Formal Name:...
| Schlagworte: | 7-[cis-4-(4-methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
| Anwendung: | ATP-competitive Lck / Src / VEGF2R / Tie-2 inhibitor |
| CAS | 479501-40-1 |
| MW: | 482.6 D |
ab 67,00 €
RK-20448
Artikelnummer: TGM-T71819-10mg
Description: RK-20448 is an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R, and Tie-2. It also inhibits BLK, Csk, Fyn, and Lyn. RK-20448 is the cis isomer of A-419259. Target: Others. Smiles: NC1=C2C(=CN(C2=NC=N1)[C@@H]3CC[C@@H](CC3)N4CCN(C)CC4)C5=CC=C(OC6=CC=CC=C6)C=C5
| Anwendung: | ATP-competitive Lck / Src / VEGF2R / Tie-2 inhibitor |
| CAS | 479501-40-1 |
| MW: | 482.62 D |
ab 104,00 €
