Zu "464-74-4" wurden 3 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Arenobufagin
Artikelnummer: LKT-A6818.1
Arenobufagin is a bufanolide steroid isolated from the Argentine toad Bufo arenarum. This compound exhibits anticancer and antiangiogenic properties, but is also cardiotoxic, inhibiting cardiovascular Na+/K+ pumps. In cellular models, arenobufagin modulated autophagy and apoptosis, inhibiting tumor growth through...
| Anwendung: | VEGFR2 inhibitor |
| CAS | 464-74-4 |
| MW: | 416.51 D |
ab 128,00 €
Arenobufagin
Artikelnummer: Cay30695-1
Arenobufagin is a cardiotonic steroid that has been found in the skin secretions of the toad B. gargarizans and has anticancer activity. It inhibits Na+/K+-ATPase activity in isolated guinea pig ventricular myocytes with an IC50 value of 290 nM. Arenobufagin (20-500 nM) induces cleavage of poly(ADP-ribose)...
| Schlagworte: | (3beta,5beta,11alpha)-3,11,14-trihydroxy-12-oxo-bufa-20,22-dienolide |
| Anwendung: | Cardiotonic steroid, anticancer bufotoxin, apoptosis inducer |
| CAS | 464-74-4 |
| MW: | 416.5 D |
ab 93,00 €
Arenobufagin
Artikelnummer: TGM-T5A2455-100mg
Description: Arenobufagin, a natural bufadienolide from toad venom, exhibits potent antineoplastic activity against HCC HepG2 cells and corresponding multidrug-resistant HepG2/ADM cells. Target: Others. Smiles: C[C@@]12[C@H](CC[C@]1(O)[C@@H]1CC[C@@H]3C[C@@H](O)CC[C@]3(C)[C@H]1[C@H](O)C2=O)c1ccc(=O)oc1. References:...
| Anwendung: | VEGFR2 inhibitor |
| CAS | 464-74-4 |
| MW: | 416.51 D |
ab 48,00 €
