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ABT-239
Artikelnummer: Cay45575-1
ABT-239 is a histamine H3 receptor antagonist (Kis = 0.316 and 1.258 nM, respectively, for the human and rat receptors). In vivo, ABT-239 (0.1-1 mg/kg) inhibits the dipsogenic response induced by (R)-(-)-alpha-methylhistamine (Cay25601) in mice. It improves social memory in adult and aged rats and attenuates...
| Schlagworte: | 4-[2-[2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl]-5-benzof uranyl]-benzonitrile |
| Anwendung: | Histamine H3 receptor antagonist |
| CAS | 460746-46-7 |
| MW: | 330.43 D |
ab 37,00 €
ABT-239
Artikelnummer: TGM-T14087-100mg
Description: ABT-239 is a novel, highly efficacious non-imidazole class histamine H3 receptor (H3R) antagonist and also acts as a transient receptor potential vanilloid type 1 (TRPV1) antagonist. Target: TRP/TRPV Channel. Smiles: C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N. References: Bhowmik M, et al. Histamine...
| CAS | 460746-46-7 |
| MW: | 330.42 D |
ab 38,00 €
