Zu "459856-18-9" wurden 2 Artikel gefunden!
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Pexacerfont
Artikelnummer: TGM-T16475-1mg
Description: Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor). Target: CRFR. Smiles: CC[C@@H](C)Nc1nc(C)nc2c(c(C)nn12)-c1ccc(OC)nc1C. References: Zhou L, et al. In vitro and in vivo metabolism and pharmacokinetics of...
| Schlagworte: | BMS-562086 |
| Anwendung: | Targets corticotropin releasing hormone receptor 1 (CRHR1) |
| CAS | 459856-18-9 |
| MW: | 340.42 D |
ab 42,00 €
Pexacerfont
Artikelnummer: Cay33221-1
Pexacerfont is an antagonist of corticotropin-releasing factor receptor 1 (CRF1, IC50 = 6.1 nM for the human receptor). It is selective for CRF1 in IMR-32 cells (mean IC50 = 10.6 nM) over CFR2beta receptors endogenously expressed in pig choroid plexus membranes (IC50 = >1,000 nM) in radioligand binding assays and...
| Schlagworte: | BMS 562086, DPC-A69448,... |
| Anwendung: | CRF1 antagonist |
| CAS | 459856-18-9 |
| MW: | 340.4 D |
ab 52,00 €
