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JNJ-7777120
Artikelnummer: Cay10011925-10
JNJ-7777120 is a potent and selective histamine H4 receptor antagonist, with a Ki value of approximately 4 nM against the human, mouse, and rat H4 receptors. Its Ki values for the histamine H1-3 receptors exceed 1 µM, regardless of species, and it has no or negligible effects on a range of other receptors and...
| Schlagworte: | (5-chloro-1H-indol-2-yl)(4-methyl-1-piperazinyl)-methanone |
| Anwendung: | Histamine H4 receptor antagonist |
| CAS | 459168-41-3 |
| MW: | 277.8 D |
ab 30,00 €
JNJ-7777120
Artikelnummer: TGM-T2232-100mg
Description: JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist with Ki of 4.5 nM, exhibits >1000-fold selectivity over the other histamin receptors. Target: Histamine Receptor. Smiles: C(=O)(C1=CC=2C(N1)=CC=C(Cl)C2)N3CCN(C)CC3. References: Jablonowski JA, et al. J Med Chem,...
| Schlagworte: | JNJ7777120 |
| Anwendung: | Histamine H4 receptor antagonist |
| CAS | 459168-41-3 |
| MW: | 277.75 D |
ab 60,00 €
