Zu "457961-34-1" wurden 2 Artikel gefunden!
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AA92593
Artikelnummer: Cay35836-10
AA92593 is an opsin 4 (OPN4) receptor antagonist (Ki = 16 nM). It inhibits light-induced calcium transients in CHO cells expressing human OPN4 (IC50 = 665 nM). AA92593 (10 µM) reverses light-induced calcium influx in rat intrinsically photosensitive retinal ganglion cells (ipRGCs). In vivo, AA92593 (30 mg/kg)...
| Schlagworte: | 1-[(4-methoxy-3-methylphenyl)sulfonyl]-piperidine |
| Anwendung: | OPN4 receptor antagonist |
| CAS | 457961-34-1 |
| MW: | 269.4 D |
ab 111,00 €
AA92593
Artikelnummer: TGM-T8566-100mg
Description: AA92593 has been used as a selective inhibitor of melanopsin. Target: Others. Smiles: COc1ccc(cc1C)S(=O)(=O)N1CCCCC1. References: Alkozi H A , Wang X , Jesus P D L M , et al. Presence of melanopsin in human crystalline lens epithelial cells and its role in melatonin synthesis[J]. Experimental Eye...
| Anwendung: | OPN4 receptor antagonist |
| CAS | 457961-34-1 |
| MW: | 269.36 D |
ab 45,00 €
