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TC-O 9311
Artikelnummer: Cay14030-1
TC-O 9311 is an agonist of the orphan G protein-coupled receptor GPR139 (EC50 = 39 nM in a calcium mobilization assay). It is selective for GPR139 over a panel of 90 additional targets. TC-O 9311 (1 µM) inhibits cell death induced by 1-methyl-4-phenylpyridinium (MPP+), but not 6-hydroxydopamine (6-OHDA, Cay-25330),...
| Schlagworte: | 3,5-dimethoxy-benzoic acid, 2-[(1-naphthalenylamino)carbonyl]hydrazide |
| Anwendung: | Potent GPR139 agonist |
| CAS | 444932-31-4 |
| MW: | 365.4 D |
ab 51,00 €
NEU
TC-O 9311
Artikelnummer: TGM-T4626L-100mg
Description: TC-O 9311 (TCO-9311) is an effective agonist of GPR139 (EC50 = 39 nM in CHO-K1 cells expressing human GPR139). Target: GPR. Smiles: COc1cc(OC)cc(c1)C(=O)NNC(=O)Nc1cccc2ccccc12. References: Shi F, Shen JK, Chen D, Fog K, Thirstrup K, Hentzer M, Karlsson JJ, Menon V, Jones KA, Smith KE, Smith G. Discovery...
| Schlagworte: | TC-O9311, TCO 9311, TCO-9311, TC-O-9311, TCO9311, TC-O 9311 |
| Anwendung: | Potent GPR139 agonist |
| CAS | 444932-31-4 |
| MW: | 365.38 D |
ab 30,00 €
