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Cyclopamine
Artikelnummer: Cay11321-10
Cyclopamine is a natural steroidal alkaloid that inhibits signaling through the hedgehog pathway at the level of the pathway activator Smoothened. By altering gene expression in this signaling sequence, cyclopamine induces defects in morphogenesis, first observed in chicks and sheep as cyclopia. As a readout of...
| Schlagworte: | 11-Deoxojervine, Jervine,... |
| Anwendung: | Pax7 inhibitor |
| CAS | 4449-51-8 |
| MW: | 411.6 D |
ab 32,00 €
Cyclopamine
Artikelnummer: TGM-T2825-100mg
Description: Cyclopamine (11-Deoxojervine), a Smoothened (Smo) antagonist (IC50: 46 nM in TM3Hh12 cells), belongs to the group of steroidal jerveratrum alkaloids. Target: Endogenous Metabolite, Hedgehog/Smoothened, Smo. Smiles:...
| Schlagworte: | 11-Deoxojervine |
| Anwendung: | Biochemical studies |
| CAS | 4449-51-8 |
| MW: | 411.62 D |
ab 48,00 €
Cyclopamine
Artikelnummer: LKT-C9710.5
A steroidal alkaloid isolated from the desert plant Veratrum californicum with both teratogenic and antitumor activities. It inhibits hedgehog/smoothened signaling.
| Schlagworte: | 11-Deoxyjervine, 11-Deoxojervine, HSDB 3505., Spiro(9H-benzo(a)fluorene-9,2'(3'H)-furo(3,2-b)pyridin)-3- ol,... |
| Anwendung: | Metabolic studies, Hedgehog inhibitor |
| CAS | 4449-51-8 |
| MW: | 411,62 D |
ab 118,00 €
Cyclopamine
Artikelnummer: AG-CN2-0028-M005
A steroidal alkaloid isolated from the desert plant Veratrum californicum with both teratogenic and antitumor activities. It inhibits hedgehog/smoothened signaling.
| Schlagworte: | 11-Deoxyjervine, 11-Deoxojervine, HSDB 3505 |
| Anwendung: | Biochemical studies |
| CAS | 4449-51-8 |
| MW: | 411,6 kD |
ab 36,00 €
