Zu "444731-52-6" wurden 5 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Pazopanib
Artikelnummer: Cay12097-10
Pazopanib is a multi-kinase inhibitor that inhibits the VEGF receptors VEGFR1, VEGFR2, and VEGFR3 (IC50s = 10, 30, and 47 nM, respectively, in a cell-free enzyme assay). It also inhibits PDGFRalpha, PDGFRbeta, and c-Kit (IC50s = 71, 84, and 74 nM, respectively, in a cell-free enzyme assay) as well as additional...
| Schlagworte: | GSK-VEG10003, GW786034B, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide |
| Anwendung: | Broad spectrum tyrosine kinase inhibitor |
| CAS | 444731-52-6 |
| MW: | 437.5 D |
ab 44,00 €
![Pazopanib, Free Base (5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methy](https://www.biomol.com/media/image/95/7c/bf/P3113-97A-25_200x200.jpg "Pazopanib, Free Base (5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methy")
Pazopanib, Free Base...
Artikelnummer: P3113-97A.25
Pazopanib is an oral, second-generation, potent and selective multi-targeted tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor and c-kit, key proteins responsible for tumor growth and angiogenesis. Pazopanib showed good potency...
| CAS | 444731-52-6 |
| MW: | 437.52 |
261,00 €
Pazopanib (free base)
Artikelnummer: AG-CR1-3746-M250
White to off-white solid. Soluble in DMSO (10mg/ml). Insoluble in water. Chemical. CAS: 444731-52-6. Formula: C21H23N7O2S. MW: 437.5. Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor. It is an orally available angiogenesis inhibitor targeting vascular endothelial growth factor...
| Schlagworte: | GW-786034, GSK-VEG10003, Votrient, Armala |
| CAS | 444731-52-6 |
| MW: | 437,5 D |
ab 33,00 €
Pazopanib
Artikelnummer: TGM-T0097L-100mg
Description: Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1, VEGFR2, VEGFR3, PDGFRbeta, c-Kit, FGFR1, and c-Fms (IC50=10/30/47/84/74/140/146 nM). Pazopanib has antitumor activity. Target: VEGFR, FGFR, c-Kit, PDGFR, Autophagy. Smiles:...
| Schlagworte: | GW786034 |
| CAS | 444731-52-6 |
| MW: | 437.52 D |
ab 40,00 €
