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(Z)-SMI-4a
(Z)-SMI-4a

Artikelnummer: TGM-T3058-100mg

Description: (Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM. Target: Pim. Smiles: FC(F)(F)C1=CC=CC(\C=C2\SC(=O)NC2=O)=C1. References: Beharry Z, et al. Mol Cancer Ther, 2009, 8(6), 1473-1483.
Schlagworte: SMI-4a, TCS PIM-1 4a
Anwendung: Pim-1/Pim-2 kinase inhibitor
CAS 438190-29-5
MW: 273.23 D
ab 46,00 €
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SMI-4a
SMI-4a

Artikelnummer: Cay11029-5

The serine/threonine Pim kinases have been suggested to promote the activity of the rapamycin-sensitive mammalian target of rapamycin (mTORC1), which regulates cell growth and survival. Pim kinases are overexpressed in solid cancers and hematologic malignancies, and as such have become targets of small molecule...
Schlagworte: 5Z-[[3-(trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione
Anwendung: Pim-1/Pim-2 kinase inhibitor
CAS 438190-29-5
MW: 273.2 D
ab 61,00 €
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SMI-4a
SMI-4a

Artikelnummer: LKT-S4932.10

Thiazolidine, Pim kinase inhibitor.
Anwendung: Thiazolidine, Pim kinase inhibitor
CAS 438190-29-5
MW: 273.23 D
ab 117,00 €
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