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Dacarbazine
Dacarbazine

Artikelnummer: TGM-T1120-100mg

Description: Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas. Target: Nucleoside Antimetabolite/Analog, Apoptosis, DNA/RNA Synthesis. Smiles: N(=NN(C)C)C1=C(C(N)=O)N=CN1. References: Serrone L, et al. J Exp Clin Cancer Res. 2000, 19(1):21-34.
Schlagworte: DTIC-Dome, Imidazole Carboxamide
CAS 4342-03-4
MW: 182.18 D
ab 33,00 €
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Dacarbazine
Dacarbazine

Artikelnummer: LKT-D0011.100

Dacarbazine is used in the treatment of malignant melanoma and sarcomas.
Anwendung: Cancer studies
CAS 4342-03-4
MW: 182,18 D
ab 120,00 €
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Dacarbazine
Dacarbazine

Artikelnummer: Cay21877-500

Dacarbazine is a DNA alkylating prodrug that is activated by P450 enzymes in liver microsomes. Following activation, it is converted, through a series of reactions, into a methyldiazonium cation that alkylates DNA at all phases of the cell cycle and induces apoptosis. In vitro, dacarbazine inhibits the growth of...
Schlagworte: NCI C04717, NSC 45388, 5-(3,3-dimethyl-1-triazen-1-yl)-1H-imidazole-4-carboxamide
Anwendung: DNA alkylating prodrug
CAS 4342-03-4
MW: 182.2 D
ab 74,00 €
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