Zu "433967-28-3" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
VU0357121
Artikelnummer: Cay22199-10
VU0357121 is a positive allosteric modulator of metabotropic glutamate receptor 5 (mGluR5) that has an EC50 value of 33 nM for the rat receptor expressed in HEK293 cells in a calcium flux assay. It is selective for mGluR5 and does not modulate responses at mGluR2-4 or mGluR6-8 but does inhibit mGluR1.Formal Name:...
| Schlagworte: | 4-butoxy-N-(2,4-difluorophenyl)-benzamide |
| Anwendung: | mGluR5 positive allosteric modulator |
| CAS | 433967-28-3 |
| MW: | 305.3 D |
ab 102,00 €
VU 0357121
Artikelnummer: TGM-T6725-100mg
Description: VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes. Target: GluR. Smiles: CCCCOC1=CC=C(C=C1)C(=O)NC1=CC=C(F)C=C1F. References: Hammond AS, et al. ACS Chem Neurosci, 2010, 1(10), 702-716.
| Anwendung: | mGluR5 positive allosteric modulator |
| CAS | 433967-28-3 |
| MW: | 305.32 D |
ab 51,00 €
