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PS-1145
Artikelnummer: Cay14862-1
PS-1145 is an IkappaB kinase beta (IKKbeta) inhibitor (IC50 = 88 nM). It selectively inhibits IKKbeta over a panel of 14 kinases (IC50s = >100 nM for all). PS-1145 also inhibits the IKK complex (IC50 = 100 nM). It inhibits the proliferation of MM.1S, U266, and RPMI-8226 myeloma cells when used at concentrations...
| Schlagworte: | IKK Inhibitor X, N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide |
| Anwendung: | IKKbeta inhibitor |
| CAS | 431898-65-6 |
| MW: | 322.8 D |
ab 49,00 €
PS-1145
Artikelnummer: TGM-T3094-100mg
Description: PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM. Target: IkappaB/IKK, Apoptosis. Smiles: Clc1cc(NC(=O)c2cccnc2)c2[nH]c3cnccc3c2c1. References: Hideshima T, et al. J Biol Chem. 2002, 277(19), 16639-16647.
| Schlagworte: | IKK Inhibitor X |
| Anwendung: | IKKbeta inhibitor |
| CAS | 431898-65-6 |
| MW: | 322.75 D |
ab 36,00 €
