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ZD 4190
Artikelnummer: Cay42248-1
A VEGFR1, VEGFR2, and EGFR inhibitor (IC50s = 0.7, 0.03, and 0.4 µM, respectively), selective for these kinases over PDGFRbeta, FGFR1, and HER2 (IC50s = 3.4, >100, and >100 µM, respectively) and MEK, Cdk2, IGF-1R, Akt, and Tie2 (IC50s = >10, >10, >20, >20, and >100 µM, respectively), selectively inhibits VEGF- or...
| Schlagworte: | N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[2-(1H-1,2,3-triazol-1-yl)ethoxy]-4-quinazolinamine |
| Anwendung: | VEGFR1/VEGFR2/EGFR inhibitor |
| CAS | 413599-62-9 |
| MW: | 459.3 D |
ab 73,00 €
ZD-4190
Artikelnummer: TGM-T5475-100mg
Description: ZD-4190 is a compound that inhibits both the vascular endothelial growth factor receptor 2 (VEGFR2) and the epidermal growth factor receptor (EGFR) signaling pathways, utilized in cancer treatment. Target: EGFR, VEGFR. Smiles: COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCn1ccnn1. References: Yang M, et al. PET...
| CAS | 413599-62-9 |
| MW: | 459.27 D |
ab 73,00 €
