Zu "408303-43-5" wurden 2 Artikel gefunden!
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GW 766994
Artikelnummer: Cay28431-1
GW 766994 is an antagonist of chemokine (C-C motif) receptor 3 (CCR3) with a Ki value of 13.8 nM in an assay of eosinophil chemotaxis induced by chemokine (C-C motif) ligand 11 (CCL11). It decreases CCL11-induced cyclin-dependent kinase 5 (Cdk5) and tau phosphorylation and production of amyloid beta (1-42) (Abeta42)...
| Schlagworte: | GW 994, 4-[[[[[[(2S)-4-[(3,4-dichlorophenyl)methyl]-2-morpholinyl]methyl]amino]carbonyl]amino]methyl]-benzamide |
| Anwendung: | CCR3 antagonist |
| CAS | 408303-43-5 |
| MW: | 451.4 D |
ab 273,00 €
GW 766994
Artikelnummer: TGM-T11521-100mg
Description: GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment. Target: CCR. Smiles: NC(=O)c1ccc(CNC(=O)NC[C@H]2CN(Cc3ccc(Cl)c(Cl)c3)CCO2)cc1. References: Neighbour H, et al. Safety and efficacy of an oral CCR3 antagonist in...
| Schlagworte: | GW 994 |
| CAS | 408303-43-5 |
| MW: | 451.35 D |
ab 1.137,00 €
