Zu "406208-42-2" wurden 2 Artikel gefunden!
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ACHP
Artikelnummer: Cay14504-1
ACHP is an inhibitor of IkappaB kinase beta (IKKbeta) and IKKalpha (IC50s = 8.5 and 250 nM, respectively). It is selective for IKKbeta and IKKalpha over IKKgamma, Syk, and MKK4 (IC50s = >20 µM for all). It reduces the constitutive phosphorylation of IkappaBalpha and NF-kappaB p65 in U266 and NCU-MM-2 multiple...
| Schlagworte: | 2-amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-(4-piperidinyl)-3-pyridinecarbonitrile |
| Anwendung: | IKKbeta / IKKalpha inhibitor |
| CAS | 406208-42-2 |
| MW: | 364.4 D |
ab 102,00 €
ACHP
Artikelnummer: TGM-T22021-25mg
Description: ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects on IKK-alpha and IKK-beta. ACHP has anti-HIV-1 activity and inhibits HIV-1 long terminal repeat (LTR)-driven gene expression through inhibition of NF-kappaB activation, inhibits TNF-alpha-induced NF-kappaB...
| Schlagworte: | IKK-2 Inhibitor VIII |
| CAS | 406208-42-2 |
| MW: | 364.44 D |
ab 46,00 €
