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Ara-G
Artikelnummer: Cay27984-100
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine (Cay-20248). Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporated into the DNA. Ara-G inhibits DNA replication by 92% after 30 minutes when used at a...
| Schlagworte: | ara-Guanosine, Guanine Arabinoside, NSC 76352, 2-amino-9-beta-D-arabinofuranosyl-1,9-dihydro-6H-purin-6-one |
| Anwendung: | Guanosine analog |
| CAS | 38819-10-2 |
| MW: | 283.2 D |
ab 49,00 €
Ara-G
Artikelnummer: TGM-T36944-100mg
Description: Ara-G is a deoxyguanosine (GdR) analog and a nucleoside analogue that is rapidly converted by cells of the T lymphoid lineage to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in inhibition of DNA synthesis and selective in vitro toxicity to T lymphoblastoid cell lines...
| CAS | 38819-10-2 |
| MW: | 283.24 D |
ab 39,00 €
