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DA-3003-1
Artikelnummer: TGM-T16357-1mg
Description: DA-3003-1 (DA-3003-1) is a membrane-permeable, potent and selective Cdc25 dual specificity phosphatase inhibitor with antitumor activity that inhibits Cdc25B2, Cdc25A, Cdc25B2 and Cdc25C. Target: Phosphatase. Smiles: ClC1=C(NCCN2CCOCC2)C(=O)c2ncccc2C1=O. References: Guo J, et al. Pharmacology and...
| Schlagworte: | NSC 663284 |
| Anwendung: | Cdc25 inhibitor |
| CAS | 383907-43-5 |
| MW: | 321.76 D |
ab 30,00 €
NSC 663284
Artikelnummer: Cay13303-1
Three genes encode dual specificity phosphatases that are Cdc25 homologs. The phosphatases, Cdc25A through C, are proto-oncogenes and are often over-expressed in cancers. NSC 663284 is a potent, cell-permeable, and irreversible inhibitor of all Cdc25 isoforms, with preference for Cdc25A (IC50 = 29, 95, and 89 nM for...
| Schlagworte: | Cdc25 Phosphatase Inhibitor II, DA-3003-1, SPS8I1, 6-chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione |
| Anwendung: | Cdc25 inhibitor |
| CAS | 383907-43-5 |
| MW: | 321.8 D |
ab 38,00 €
