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HPA-12
Artikelnummer: Cay28350-25
HPA-12 is a ceramide analog and inhibitor of ceramide transfer protein (CERT). It inhibits binding of a ceramide probe to the isolated steroidogenic acute regulatory protein-related lipid transfer (START) domain of CERT with an EC50 value of 4 µM in a TR-FRET assay. HPA-12 (2.5 µM) inhibits conversion of the...
| Schlagworte: | (1R,3S)-HPA-12, N-[(1R,3S)-3-hydroxy-1-(hydroxymethyl)-3-phenylpropyl]-dodecanamide |
| Anwendung: | Ceramide analog, ceramide transfer protein (CERT) inhibitor |
| CAS | 383418-30-2 |
| MW: | 363.5 D |
ab 366,00 €
HPA-12
Artikelnummer: TGM-T71843-5mg
Description: HPA-12 is a novel potent inhibitor of cert, binding to the ceramide-binding pocket in the cert start domain. Target: Others. Smiles: CCCCCCCCCC CC(=O)N[C@@H](CO)C[C@H](O)c1ccccc1
| Anwendung: | Ceramide analog, ceramide transfer protein (CERT) inhibitor |
| CAS | 383418-30-2 |
| MW: | 363.53 D |
815,00 €
