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Saracatinib
Artikelnummer: Cay11497-5
Saracatinib is a dual inhibitor of the tyrosine kinases c-Src and Abl (IC50 = 2.7 and 30 nM, respectively). It less effectively inhibits other receptor and non-receptor tyrosine kinases as well as assorted serine/threonine kinases. Saracatinib is orally available and blocks cell motility, migration, adhesion,...
| Schlagworte: | AZD 0530,... |
| Anwendung: | c-Src / Abl inhibitor |
| CAS | 379231-04-6 |
| MW: | 542 D |
ab 48,00 €
![Saracatinib, Free Base (N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(ox](https://www.biomol.com/media/image/c3/9d/7b/S0097-50-10_200x200.jpg "Saracatinib, Free Base (N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(ox")
Saracatinib, Free Base...
Artikelnummer: S0097-50.10
Saracatinib an orally available Src kinase inhibitor. Saracatinib inhibits c-Src and Abl enzymes at low nanomolar concentrations. Saracatinib blocked the tumor growth of a c-Src-transfected 3T3-fibroblast xenograft in vivo and increased significantly the survival of animals in a highly aggressive model of human...
| CAS | 379231-04-6 |
| MW: | 542.03 |
241,00 €
Saracatinib
Artikelnummer: TGM-T6078-100mg
Description: Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes. Target: BTK, Src, EGFR, Autophagy. Smiles: CN1CCN(CCOc2cc(OC3CCOCC3)c3c(Nc4c5OCOc5ccc4Cl)ncnc3c2)CC1. References: Green TP, et al. Preclinical anticancer activity of the...
| Schlagworte: | AZD0530 |
| Anwendung: | Targets abelson tyrosine-protein kinase 1 [EC:2.7.10.2] (ABL1) |
| CAS | 379231-04-6 |
| MW: | 542.03 D |
ab 56,00 €
